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KB's  FROM THE PETRI DISH's avatar

Very interesting take on Vitamin D, I came across that VITAL-Telomere study earlier today but 2000 IU seems a bit high. The conclusion was "potential benefits of vitamin D on biological aging and age-related diseases." This study group was in the "elderly" category that might benefit since they experience decrease production in skin production and and reduction from age-related renal function. So it seems that supplementation is a good idea. They mentioned the need for larger studies with more diverse population. I consider this low evidence but older folks would likely benefit from supplementation. https://link.springer.com/article/10.1007/s12020-022-03208-3

Like to make a note that any supplement should have third party lab certification. This is a good guideline.

In terms of exercise, a fat soluble vitamin stored in adipose tissue released with exercise seems logical but we still needed to do the science. Ginger foot pads? Might make me think of a ginger curry dish while attached to my foot.

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Mactoul's avatar

Some research suggests that high levels of d3 are associated with greater risk of pancreatic/prostate cancer. This risk depends strongly on latitude ie avg uv levels.

There are also reports that calcium metabolism requires less d3 when grain consumption is greatly reduced thus eliminating the need to supplement d3.

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